Review of Bioequivalence Testing for Reclamation of Strip
Department of Statistics
Colorado State University
Monday, 24 March 2003
Room 005, Statistics Building
In the demanding world of the 21st century, everything changes and evolves.
What was right yesterday, might not be today. Statistics is not exception
to these rules. This paper introduces the term bioequivalence, explains
how it might be used by the Department of Environmental Quality, and
it also compares the classical null hypothesis with the bioequivalence
test. Specifically, this paper tries to look at the possible problems
with the classical null hypothesis, and why bioequivalence testing might
be a preferred method when dealing with the bond release data. Currently,
the state of Wyoming is in the process of reviewing and re-writing the
Appendix A of the Coal Mine’s Rules and Regulations. We would
like to provide a scientific basis for changes in this Appendix.
By the means of simulation, we will try show when and why the bioequivalence
might be a preferred method over the classical null hypothesis. The
data sets used in the project were provided by the states of Wyoming,
Colorado, and New Mexico.